<small id="f2xv5"></small>

  •
    • <cite id="f2xv5"></cite>

        



        
  
        
  	
        
    	
        德思特生物專注于中藥（植物藥）物質基礎研究以及天然化合物、中藥化學對照品實物生產供應
        
        
    
        
  
        
  
  
        
	
        
    
    

        天然藥物活性單體及中藥對照品專業生產供應商

        
    
        聯系方式
        028-85003950
        
    
        
   
        
   
   
        
   	  
    
        

        



        
	
        
		
	
        

        




        
	
        
   	  
    


        
        
        
        	
        
        		
                
                
                
                
        
                	
        聯系方式
        
                	
        
                    	
        服務熱線：
        028-8500-3950
        公司傳真：028-85589956
        公司郵箱：sales@tcmlmt.com
        公司網址：m.chuaihan.com
        公司地址：四川省成都市溫江區?？坡肺鞫?28號5棟

                            
        
                
        
                
        	
        
            
        
            
        		
        
                	  
        
                        
        發表文獻展示
        
                        當前位置:首頁關于德思特 > 發表文獻展示 > 
                      
        
                      
        
                   		  
        
                   		  		
        Neurochemical Research-14 May 2020  羥基紅花黃色素A 78281-02-4
        
                   		  		
        時間：2020-09-03   瀏覽次數：  分享到：
        
                   		  			
        
                   		  		
        
                   		  		
        
                   		  			
        afflower Yellow Improves the Synaptic Structural Plasticity by Ameliorating the Disorder of Glutamate Circulation in Aβ1-42-induced AD Model Rats
        
期刊名：Neurochemical Research
        
文獻編號：10.1007/s11064-020-03051-w
        
文獻地址：https://link.springer.com/article/10.1007/s11064-020-03051-w
        
發表日期：14 May 2020
        


        Abstract
        
Safflower yellow (SY) is the main effective component of Carthamus tinctorius L., and Hydroxysafflor yellow A (HSYA) is the single active component with the highest content in SY. SY and HSYA have been shown to have neuroprotective effects in several AD models. In this study, we aimed to clarify whether the effects of SY and HSYA on the learning and memory abilities of Aβ1-42-induced AD model rats are related to the enhancement of synaptic structural plasticity in brain tissues and the amelioration of disorder of glutamate circulation. We used rats injected with Aβ1-42 into the bilateral hippocampus as a model of AD. After treatment with SY and HSYA, the learning and memory abilities of the Aβ1-42-induced AD model rats were enhanced, Aβ deposition in the AD model rats was decreased, structural damage to dendritic spines and the loss of synaptic-associated proteins were alleviated, and the disorder of glutamate circulation was ameliorated. The results indicated that SY and HSYA improve synaptic structural plasticity by ameliorating the disorder of glutamate circulation in Aβ1-42-induced AD model rats.
        

        
Hydroxysafor yellow A  （HSYA purity>98%) was purchased from Chengdu DeSiTe  Biological Technology Co., Ltd. (Sichuan, China).
        
                   		  		
        
                   		  		
                   		  
        
                      	  
                      
        
                
        
                
                
        
                	
        
                        
        熱門新聞
        
                    
        
                    
        
                        					                                                  
        
                            
                            
        
                                
        Afrormosine CAS:550-79-8 中藥對照品標準品
        
                                
        產品編碼：DA0040產品名稱：Afrormosine英文名:AfrormosineCAS登錄...
        
                                查看更多
                            
        
                        
        
                        
          
                                                   
        
                                                                    
        
                    
                    
                
        
                
        	
        
        
        
        
    
        

        










        
	
        
	
        
        
        
        
    
        

        


        
	
        
		
    
        
    
        
		
        
		 
        德思特
        
		 
        
		 	版權所有：成都德思特生物技術有限公司 Copyright © 2016   蜀ICP備16023840號-2
        
公司地址：四川省成都市溫江區?？坡肺鞫?28號5棟
        
公司電話：028-85003950
        

        
		 
        
		 
        掃一掃關注德思特
           掃碼關注公眾號
         
        
		
        		
	
        	

        
 
     
     
     
     





四虎国产永久免费久久_狠狠躁夜夜躁人人爽天天30人_成人动漫在线免费观看_久久婷婷激情综合色综合俺也去

        <small id="f2xv5"></small>
      2. 

        

        4. <cite id="f2xv5"></cite>